ISSN: 2149-2247 | E-ISSN: 2149-2549
Erciyes Medical Journal The Overlap of Sarcopenia and Frailty: When Two Major Geriatric Syndromes Coincide [Erciyes Med J]
Erciyes Med J. 2022; 44(6): 555-559 | DOI: 10.14744/etd.2022.96777

The Overlap of Sarcopenia and Frailty: When Two Major Geriatric Syndromes Coincide

Esma Nur Kolbaşı1, Filiz Demirdağ2, Gözde Balkaya3, Özlem Pehlivan4, Sema Basat3
1Department of Palliative Care, University of Health Sciences, Ümraniye Training and Research Hospital, İstanbul, Türkiye
2Department of Physiotherapy and Rehabilitation, İstanbul Medeniyet University Faculty of Health Sciences, İstanbul, Türkiye
3Department of Internal Medicine, University of Health Sciences, Ümraniye Training and Research Hospital, İstanbul, Türkiye
4Department of Rheumatology, University of Health Sciences, Ümraniye Training and Research Hospital, İstanbul, Türkiye

Objective: The aim of this study was to investigate the prevalence of the co-occurrence of sarcopenia and frailty and to determine any associations between these syndromes and physical activity, nutrition, and psychological well-being in Turkish older adults.
Materials and Methods: All of the participants were aged ≥65 years. Sarcopenia was diagnosed using the SARC-CalF scale with a previously determined national calf diameter cut-off value of 33 cm. Frailty was evaluated with the FRAIL scale. The Rapid Assessment of Physical Activity (RAPA) was administered to measure physical activity, the Mini-Nutritional Assessment (MNA) to evaluate nutritional status, and the Geriatric Depression Scale (GDS) to assess depression.
Results: A total of 566 individuals were included in the study. The prevalence rate of pre-frailty, sarcopenia, frailty, and sarcopenia+frailty was 42.4%, 6.89%, 6.89%, and 2.47%, respectively. A multinomial logistic regression model consisting of the RAPA (p<0.0001), MNA (p<0.0001), and GDS (p<0.0001) revealed that each was associated with all of the subgroups (pseudo R2=0.322; goodness-of-fit= 0.753; p=0.481). The association became stronger with progression from pre-frailty to sarcopenia+frailty, with the exception of the RAPA score recorded in the sarcopenia subgroup.
Conclusion: The concurrent prevalence rate of sarcopenia and frailty was 2.47% in community-dwelling older adults. The likelihood of being physically inactive, malnourished, and depressed became more pronounced with deterioration in physical condition. This is the first known study to report the prevalence rate of the overlap of frailty and sarcopenia in Türkiye and the association between these syndromes and physical inactivity, malnutrition, and depression. The study has been registered with the US National Institutes of Health (National Clinical Trial number: NCT04146844).

Keywords: Depression, frail elderly, healthy diet, geriatrics, sarcopenia, sedentary behavior.

Esma Nur Kolbaşı, Filiz Demirdağ, Gözde Balkaya, Özlem Pehlivan, Sema Basat. The Overlap of Sarcopenia and Frailty: When Two Major Geriatric Syndromes Coincide. Erciyes Med J. 2022; 44(6): 555-559

Corresponding Author: Esma Nur Kolbaşı, Türkiye
Manuscript Language: English
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