ISSN: 2149-2247 | E-ISSN: 2149-2549
Erciyes Medical Journal Metastatic Esophagogastric Junction Adenocarcinoma Masquerading as Primary Thyroid Malignancy: A Case Report [Erciyes Med J]
Erciyes Med J. 2021; 43(6): 614-616 | DOI: 10.14744/etd.2020.82085

Metastatic Esophagogastric Junction Adenocarcinoma Masquerading as Primary Thyroid Malignancy: A Case Report

Geng Ju Tuang1, Abdul Ruhiulazim Liman2, Najihah Nordin2, Jennifer Peak Hui Lee2, Salmi Abdullah3
1Department of Otorhinolaryngology, Head and Neck Surgery, Hospital Selayang, Batu Caves, Malaysia
2Department of Otorhinolaryngology, Head and Neck Surgery, University Kebangsaan Malaysia Medical Centre, Selangor, Malaysia
3Department of Pathology, Hospital Selayang, Batu Caves, Malaysia

Background: Distant metastasis of neoplasm to the thyroid gland represents an unusual clinical manifestation, especially in an individual without a prior history of malignancy. The most frequent site of origin is the renal system, followed by the respiratory system. Metastatic spread from the gastro-digestive tract is rare, and it mostly occurs from the colorectum.
Case Report: A 70-year-old woman presented with thyroid swelling and right vocal fold paralysis that have been going on for 6 months in the absence of upper digestive tract symptoms. Ultrasound-guided biopsy revealed metastatic adenocarcinoma. Its origin was confirmed through an endoscopic biopsy of an exophytic mass forming from the cardioesophageal junction. Computed tomography staging revealed an advanced-stage disease, with metastatic deposits over multiple organs. The patient was given palliative chemotherapy and supportive treatment. She succumbed to death at 1 month post-diagnosis.
Conclusion: Secondary thyroid malignancy represents a rare entity and should be contemplated as one of the differential diagnoses of a goiter. A thorough workout should be performed in atypical thyroid malignancy to avoid unnecessary thyroidectomies in widespread metastasis.

Keywords: Thyroid, neoplasm metastasis, esophagogastric junction.

Geng Ju Tuang, Abdul Ruhiulazim Liman, Najihah Nordin, Jennifer Peak Hui Lee, Salmi Abdullah. Metastatic Esophagogastric Junction Adenocarcinoma Masquerading as Primary Thyroid Malignancy: A Case Report. Erciyes Med J. 2021; 43(6): 614-616

Corresponding Author: Geng Ju Tuang, Malaysia
Manuscript Language: English
LookUs & Online Makale