ISSN: 2149-2247 | E-ISSN: 2149-2549
Volume : 44 Issue : 4 Year : 2022
Erciyes Medical Journal Level of Serum Adiponectin in Sjögren’s Syndrome [Erciyes Med J]
Erciyes Med J. 2019; 41(2): 186-190 | DOI: 10.14744/etd.2019.26214

Level of Serum Adiponectin in Sjögren’s Syndrome

Kübra Doğan1, Muhammed Emre Urhan2, Şeymanur Yıldız3, Mehmet Emin Derin2, Ali Şahin2, Halef Okan Doğan3
1Department of Biochemistry, Numune Hastanesi, Sivas, Turkey
2Department of Internal Medicine, Cumhuriyet University Faculty of Medicine, Sivas, Turkey
3Department of Biochemistry, Cumhuriyet University Faculty of Medicine, Sivas, Turkey

Objective: To evaluate the serum adiponectin level and determine the association between adiponectin and various clinical and laboratory findings in patients with primary Sjögren’s syndrome (pSS).
Materials and Methods: A total of 50 patients and 30 healthy volunteers were enrolled in the present study. Serum adiponectin levels were detected by colorimetric enzyme-linked immunosorbent assay. The medical history of patients including complete blood count analysis; high sensitive C-reactive protein; erythrocyte sedimentation rate (ESR); complement component 3; complement component 4; low density lipoprotein cholesterol; triglyceride; immunoglobulin G (IgG), IgA, and IgM levels; and the status of Ro 60, Ro 52, Sjögren’s syndrome A, Sjögren’s syndrome B, and rheumatoid factor were obtained from laboratory information system.
Results: Serum adiponectin levels were 2.34 (0.77–4.95) ng/mL and 1.73 (0.01–7.76) ng/mL in patients and controls, respectively (p=0.316). Positive correlation was observed between the values of serum adiponectin, ESR (p=0.013, rho=0.362), and body mass index (p=0.018, rho=0.362) in patients.
Conclusion: These findings indicate that adiponectin does not play a crucial role in the immunological and clinical patterns of pSS.

Keywords: Sjögren’s syndrome, adiponectin, serum

Kübra Doğan, Muhammed Emre Urhan, Şeymanur Yıldız, Mehmet Emin Derin, Ali Şahin, Halef Okan Doğan. Level of Serum Adiponectin in Sjögren’s Syndrome. Erciyes Med J. 2019; 41(2): 186-190

Corresponding Author: Kübra Doğan, Türkiye
Manuscript Language: English
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