ISSN: 2149-2247 | E-ISSN: 2149-2549
Erciyes Medical Journal Human Herpesvirus 7-Associated Acute Longitudinal Myelitis in an Immunocompetent Patient: A Case Report [Erciyes Med J]
Erciyes Med J. 2022; 44(3): 339-343 | DOI: 10.14744/etd.2021.17802

Human Herpesvirus 7-Associated Acute Longitudinal Myelitis in an Immunocompetent Patient: A Case Report

Müge Kuzu Kumcu1, Zehra Yavuz2, Ebru Us3, Hüseyin Özden Şener2
1Department of Neurology, Lokman Hekim University Faculty of Medicine, Ankara, Turkey; Department of Neurology, Ankara University Faculty of Medicine, Ankara, Turkey
2Department of Neurology, Ankara University Faculty of Medicine, Ankara, Turkey
3Department of Microbiology, Ankara University Faculty of Medicine, Ankara, Turkey

Background: Human herpesvirus 7 (HHV-7) can cause a central nervous system infection in both immunodeficient and immunocompetent patients. This report describes a case of longitudinal myelitis due to HHV-7.
Case Report: A 56-year-old male presented with lower extremity weakness and the inability to walk, difficulty urinating, and numbness in lower chest region. Thoracic magnetic resonance imaging showed hyperintensity in the spinal cord below the T4 level in a T2 sequence. Polymerase chain reaction (PCR) analysis of the cerebrospinal fluid (CSF) revealed HHV-7. The clinical diagnosis was longitudinal myelitis and a positive PCR test confirmed acute viral longitudinal myelitis due to HHV-7. Treatment with intravenous immunoglobulin and ganciclovir was initiated. After a program of rehabilitation therapy, the patient demonstrated partial recovery at a 9-month follow-up assessment.
Conclusion: Acute transverse myelitis due HHV-7 has been reported, but clinicians should be aware that, while rare, longi-tudinal myelitis can also occur, even in an immunocompetent patient.

Keywords: Epstein-Barr virus, human herpesvirus 7, immunocompetent, viral myelitis.

Müge Kuzu Kumcu, Zehra Yavuz, Ebru Us, Hüseyin Özden Şener. Human Herpesvirus 7-Associated Acute Longitudinal Myelitis in an Immunocompetent Patient: A Case Report. Erciyes Med J. 2022; 44(3): 339-343

Corresponding Author: Müge Kuzu Kumcu, Türkiye
Manuscript Language: English
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