ISSN: 2149-2247 | E-ISSN: 2149-2549
Erciyes Medical Journal Is it Worth Using Thrombolytic Therapy in Elderly Patients with Pulmonary Embolism? [Erciyes Med J]
Erciyes Med J. 2021; 43(5): 433-437 | DOI: 10.14744/etd.2021.01460

Is it Worth Using Thrombolytic Therapy in Elderly Patients with Pulmonary Embolism?

Neslihan Özçelik, Songül Özyurt, Bilge Yilmaz Kara, Dilek Karadoğan, Aziz Gümüş, Ünal Şahin
Department of Chest Diseases, Recep Tayyip Erdoğan University, Rize, Turkey

Objective: Antithrombotic treatment is avoided in geriatric population owing to its side effects. Thus, we aimed to examine complication rates related to thrombolytic treatment in geriatric patients with pulmonary thromboembolism (PTE).
Materials and Methods: The study included patients aged >65 years who received thrombolytic treatment for a diagnosis of PTE. Patient files were screened retrospectively to extract data on etiology, clinical risk scores, laboratory values, thrombolytic treatment-related complications, and early mortality development.
Results: The study included 68 patients (female: 70.6%; mean age: 77.8 years). The Simplified Pulmonary Embolism Severity Index score was high in all patients. Early mortality risk classification at admission was high, medium-high, and medium-low risk in 64.7%, 23.5%, and 11.8% patients, respectively. In-hospital mortality was 30.9%. The causes of death were secondary to PTE in 85.7% patients, respiratory failure in 9.6%, and sepsis in 4.7%. Complication-related mortality was not observed. The only independent risk factor for mortality was change in consciousness.
Conclusion: Mortality and complication rates in geriatric patients receiving thrombolytic treatment are not as high as expected.

Keywords: Change of consciousness, geriatric patients, pulmonary embolism, thrombolytic therapy

Neslihan Özçelik, Songül Özyurt, Bilge Yilmaz Kara, Dilek Karadoğan, Aziz Gümüş, Ünal Şahin. Is it Worth Using Thrombolytic Therapy in Elderly Patients with Pulmonary Embolism?. Erciyes Med J. 2021; 43(5): 433-437

Corresponding Author: Neslihan Özçelik, Türkiye
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