ISSN: 2149-2247 | E-ISSN: 2149-2549
Volume : 44 Issue : 1 Year : 2022
Management of Acute Kidney Injury in a Patient with Diabetic Ketoacidosis and Multiple Autoimmune Diseases [Erciyes Med J]
Erciyes Med J. 2022; 44(1): 102-105 | DOI: 10.14744/etd.2021.92489

Management of Acute Kidney Injury in a Patient with Diabetic Ketoacidosis and Multiple Autoimmune Diseases

Emre Sarıkaya1, Gül Direk1, Serkan Özsoylu2, Ismail Dursun3, Nihal Hatipoğlu1
1Department of Pediatric Endocrinology, Erciyes University Faculty of Medicine, Kayseri, Turkey
2Department of Pediatric Intensive Care, Erciyes University Faculty of Medicine, Kayseri, Turkey
3Department of Pediatric Nephrology, Erciyes University Faculty of Medicine, Kayseri, Turkey

Background: Type 1 diabetes mellitus (DM) is an autoimmune disease caused by the failure of pancreatic beta cells to secrete sufficient insulin. Several other autoimmune diseases that involve the endocrine glands may accompany type 1 DM. Prerenal acute kidney injury due to dehydration occurring during diabetic ketoacidosis (DKA) is a common condition that usually im-proves with appropriate fluid therapy management.
Case Report: A 9-year-old child presented with DKA and renal failure that was resistant to treatment. Other autoimmune conditions potentially accompanying the DM were investigated and it was determined that the patient had severe hypothy-roidism due to Hashimoto’s thyroiditis. The hypothyroidism was the cause of the treatment-resistant renal failure, which regressed within days of starting levothyroxine treatment.
Conclusion: In addition to classic causes of renal failure in patients with diabetes, it is important to remember the potential effects of other underlying autoimmune events, such as hypothyroidism.

Keywords: Acute kidney injury, autoimmunity, diabetic ketoacidosis, Hashimoto’s thyroiditis

Emre Sarıkaya, Gül Direk, Serkan Özsoylu, Ismail Dursun, Nihal Hatipoğlu. Management of Acute Kidney Injury in a Patient with Diabetic Ketoacidosis and Multiple Autoimmune Diseases. Erciyes Med J. 2022; 44(1): 102-105

Corresponding Author: Nihal Hatipoğlu, Türkiye
Manuscript Language: English
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