ISSN: 2149-2247 | E-ISSN: 2149-2549
Volume : 45 Issue : 1 Year : 2023
Anti-GQ1b Negative Miller Fisher Syndrome Mimicking Acute Sphenoid Sinusitis [Erciyes Med J]
Erciyes Med J. Ahead of Print: EMJ-80932 | DOI: 10.14744/etd.2022.80932

Anti-GQ1b Negative Miller Fisher Syndrome Mimicking Acute Sphenoid Sinusitis

Kuganathan Ramasamy1, Jeyasakthy Saniasiaya2, Norhaslinda Abdul Gani1
1Department of Otorhinolaryngology-Head & Neck Surgery, Hospital Tuanku Ja’afar Seremban, Negeri Sembilan, Malaysia
2Department of Otorhinolaryngology-Head & Neck Surgery, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia

Introduction: Miller Fisher Syndrome is a variant of Guillain-Barre Syndrome, classically characterized by triad of ataxia, areflexia and ophthalmoplegia. However, many conditions can masquerade the presentation of Miller Fisher Syndrome, potentially leading to grave consequences due to delayed diagnosis or even misdiagnosis.
Case report: Presently described is a case of Miller Fisher Syndrome mimicking acute sphenoid sinusitis with intracranial complication, in an otherwise healthy 19-year-old gentleman. Nevertheless, accurate diagnosis with prompt treatment led to full clinical recovery of our patient.
Conclusion: Sphenoid sinusitis warrants great vigilance and thorough neurological examination due to its proximity to structures such as cavernous sinus and its associated cranial nerves. This case highlights its potential to mask more devastating condition like Miller Fisher Syndrome and successful role of medical management without need for sphenoidotomy

Keywords: Miller Fisher syndrome, Guillain-Barre Syndrome; sinusitis; sphenoid sinusitis; ophthalmoplegia



Corresponding Author: Kuganathan Ramasamy, Malaysia
Manuscript Language: English
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