ISSN: 2149-2247 | E-ISSN: 2149-2549
Volume : 43 Issue : 6 Year : 2021
The Role of Platelet Count, Platelet Lymphocyte Ratio, and Systemic Immune-Inflammatıon Index in Predicting Lymph Node Metastasis in Colon Cancer [Erciyes Med J]
Erciyes Med J. 2021; 43(6): 548-553 | DOI: 10.14744/etd.2021.67689

The Role of Platelet Count, Platelet Lymphocyte Ratio, and Systemic Immune-Inflammatıon Index in Predicting Lymph Node Metastasis in Colon Cancer

Serhan Yılmaz, Hakan Bölükbaşı, Engin Okan Yıldırım, Aziz Ocakoğlu, Mehmet Abdussamet Bozkurt
Department of General Surgery, University of Health Sciences, Kanuni Sultan Süleyman Training and Research Hospital, İstanbul, Turkey

Objective: This study aimed to evaluate the role of platelet counts, platelet lymphocyte ratio, neutrophil lymphocyte ratio, and systemic immune-inflammation index in predicting lymph node metastasis in preoperative period in patients with colon cancer.
Materials and Methods: This study was conducted between May 2015 and May 2020 at the University of Health Sciences, Kanuni Sultan Suleyman Training and Research Hospital. A total of 130 patients who underwent colon resection for colon adenocarcinoma were evaluated. They were divided into groups via nodal staging using the TNM classification: N0: 0; N1: 1–3; and N2: 4 or more.
Results: A significant difference was observed between the inter-group platelet counts, platelet lymphocyte ratio, and systemic immune-inflammation index. The platelet value was significantly higher in N1 and N2 than in N0. There was also a significant difference between NO and N2 compared with platelet lymphocyte ratio and systemic immune-inflammation index.
Conclusion: Systemic immune-inflammation index, platelet lymphocyte ratio, and platelet count can be used in combination with TNM staging for personalized treatment.

Keywords: Systemic immune-inflammation index, platelet lymphocyte ratio, platelet counts, lymph node metastasis, colon cancer.

Serhan Yılmaz, Hakan Bölükbaşı, Engin Okan Yıldırım, Aziz Ocakoğlu, Mehmet Abdussamet Bozkurt. The Role of Platelet Count, Platelet Lymphocyte Ratio, and Systemic Immune-Inflammatıon Index in Predicting Lymph Node Metastasis in Colon Cancer. Erciyes Med J. 2021; 43(6): 548-553

Corresponding Author: Hakan Bölükbaşı, Türkiye
Manuscript Language: English
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