ISSN: 2149-2247 | E-ISSN: 2149-2549
Volume : 43 Issue : 5 Year : 2021
Evaluation of the Effect of Type 1 and Type 2 Diabetes Mellitus without Diabetic Retinopathy on Subfoveal Choroidal Thickness and Central Macular Thickness in Adolescents [Erciyes Med J]
Erciyes Med J. 2021; 43(4): 379-384 | DOI: 10.14744/etd.2020.05695

Evaluation of the Effect of Type 1 and Type 2 Diabetes Mellitus without Diabetic Retinopathy on Subfoveal Choroidal Thickness and Central Macular Thickness in Adolescents

Mustafa Hepokur1, Hamdi Cihan Emeksiz2, Merve Nur Hepokur2, Ayşe Aşık3, Halit Oğuz1
1Department of Ophthalmology, İstanbul Medeniyet University Faculty of Medicine, Göztepe Prof. Dr. Süleyman Yalçın City Hospital, İstanbul, Turkey
2Department of Pediatric Endocrinology, İstanbul Medeniyet University Faculty of Medicine, Göztepe Prof. Dr. Süleyman Yalçın City Hospital, İstanbul, Turkey
3Department of Pediatry, İstanbul Medeniyet University Faculty of Medicine, Göztepe Prof. Dr. Süleyman Yalçın City Hospital, İstanbul, Turkey

Objective: Evaluation of the effect of Type 1 and Type 2 diabetes mellitus (DM) without diabetic retinopathy on subfoveal choroidal thickness (SCT) and central macular thickness (CMT) in adolescents.
Materials and Methods: This prospective cohort study included a total of 70 eyes of 35 patients and 42 eyes of 21 age-matched healthy control individuals. SCT and CMT were measured in all participants using enhanced depth imaging-optical coherence tomography.
Results: Forty eyes of 20 patients with Type 1 DM, 30 eyes of 15 patients with Type 2 DM and 42 eyes of 21 healthy controls were examined. SCT was significantly lower in type 1 DM group than in type 2 DM group (p=0.008). CMT did not significantly differ among the three groups (p=0.412). SCT and CMT did not correlate with HbA1c, BMI, fasting blood glucose, HDL, LDL, total cholesterol and triglycerides levels and also duration of diabetes.
Conclusion: We revealed that the SCT was significantly thinner in Type 1 diabetic adolescents than type 2 DM. Larger series and further studies are needed to better demonstrate this different effect on choroidal layer.

Keywords: dolescence, central macular thickness, diabetes mellitus, enhanced depth imaging-optical coherence tomography, subfoveal choroidal thickness.

Mustafa Hepokur, Hamdi Cihan Emeksiz, Merve Nur Hepokur, Ayşe Aşık, Halit Oğuz. Evaluation of the Effect of Type 1 and Type 2 Diabetes Mellitus without Diabetic Retinopathy on Subfoveal Choroidal Thickness and Central Macular Thickness in Adolescents. Erciyes Med J. 2021; 43(4): 379-384

Corresponding Author: Mustafa Hepokur, Türkiye
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