ISSN 2149-2247 | E-ISSN 2149-2549
Original Investigation
The Role of Diffusion-Weighted MR Imaging in Detecting Malignant and Benign Pleural Thickening in Asbestos-Related Pleural Diseases
1 Department of Radiology, Firat University Faculty of Medicine, Elazığ, Turkey  
Erciyes Med J 2017; 39: 44-47
DOI: 10.5152/etd.2017.16045
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Key Words: Diffusion-weighted imaging, ADC measurement, pleura, asbestosis, mesothelioma
Abstract

Objective: The aim of this study was to evaluate the role of diffusion-weighted magnetic resonance imaging (dMRI) in differentiating between diffuse malignant and benign pleural thickening in asbestos-related pleural diseases.

 

Materials and Methods: Sixty-two patients were included in the study. Thirty-two had a benign form and 30 had malignant pleural mesothelioma (MPM). The patient files and records belonging to those who underwent dMRI on a 1.5 T MR system between May 2014 and January 2016 in our clinic were examined retrospectively. The dMRI was performed with 0, 500, and 1000 mm2/s b-values. The apparent diffusion coefficient (ADC) map was generated, and means ADC values were determined from measurements of pleural thickening.

 

Results: The mean ADC values were 1.94±0.09×10-3 mm2/s and 0.84±0.05×10-3 mm2/s in benign pleural disease and MPM, respectively. The mean ADC value in the malignant group was significantly lower than in the benign group (p<0.05).

 

Conclusion: Our results show that dMRI and ADC values are useful for differentiating between benign and malignant pleural thickening in asbestos-related pleural diseases. dMRI gives clues for the interpretation of whether pleural thickening is benign or malignant and can assist in the early detection of MPM.

 

Cite this article as: Koç M, Poyraz AK. The Role of Diffusion-Weighted MR Imaging in Detecting Malignant and Benign Pleural Thickening in Asbestos-Related Pleural Diseases. Erciyes Med J 2017; 39(2): 44-7.

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